Survival after Veno-Arterial ECMO Score

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SAVE Score Calculator – VA ECMO

SAVE Score Calculator

Survival After Veno-Arterial ECMO score for adult patients receiving VA ECMO for refractory cardiogenic shock.

Clinical caution: This calculator is for education and audit support only. It should not replace specialist ECMO team assessment, local protocols, or clinical judgment.

Patient factors

Etiology of cardiogenic shock

Renal and metabolic factors

Defined as acute renal insufficiency, e.g. creatinine >1.5 mg/dL / 132.6 µmol/L, with or without RRT.
Kidney damage or GFR <60 mL/min/1.73 m² for ≥3 months.
Worst value within 6 hours before ECMO cannulation.

Respiratory factors

Cardiac factors

Worst value within 6 hours before ECMO cannulation.
Worst value within 6 hours before ECMO cannulation.

Other organ failures before ECMO

Bilirubin ≥33 µmol/L / 1.9 mg/dL, or ALT/AST >70 IU/L.
Includes neurotrauma, stroke, encephalopathy, cerebral embolism, seizure, and epileptic syndromes.

Result

SAVE score —
Risk class —
Estimated survival to discharge —
Score breakdown
  • No calculation yet.

Risk-class interpretation

  • Class I: SAVE score ≥5; estimated survival 75%
  • Class II: SAVE score 1 to 4; estimated survival 58%
  • Class III: SAVE score −4 to 0; estimated survival 42%
  • Class IV: SAVE score −9 to −5; estimated survival 30%
  • Class V: SAVE score ≤−10; estimated survival 18%

These are class-level estimates from the published SAVE model, not an individualized guarantee.

References

  1. Schmidt M, Burrell A, Roberts L, et al. Predicting survival after ECMO for refractory cardiogenic shock: the Survival After Veno-Arterial ECMO (SAVE)-score. European Heart Journal. 2015;36(33):2246–2256. doi:10.1093/eurheartj/ehv194
  2. Extracorporeal Life Support Organization (ELSO). SAVE Score for VA ECMO. https://www.elso.org/savescore/index.html
  3. MDCalc. SAVE (Survival after Veno-Arterial ECMO) Score. https://www.mdcalc.com/calc/10144/save-survival-veno-arterial-ecmo-score

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