Stool Osmolar Gap Calculator

Stool Osmotic Gap Calculator

Stool Osmotic Gap Calculator

Use stool sodium and potassium concentrations to estimate whether chronic diarrhea is more likely osmotic, secretory, or indeterminate in pattern.

Result

Stool Osmotic Gap:

Formula Stool Osmotic Gap = 290 − 2 × (Stool Na+ + Stool K+)
Interpretation
  • < 50 mOsm/kg: suggests secretory diarrhea
  • 50–100 mOsm/kg: indeterminate / mixed pattern
  • > 100 mOsm/kg: suggests osmotic diarrhea

This calculator is for educational and clinical support purposes only. Results should be interpreted with the patient’s history, examination, medication use, diet, stool collection quality, and other investigations.

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