Central Nervous System International Prognostic Index (CNS-IPI)
Predicts the risk of central nervous system relapse in patients with diffuse large B-cell lymphoma (DLBCL).
CNS-IPI Score
0 / 6
Low Risk
Score 0–1
Approximate 2-year CNS relapse risk: 0.6%
Intermediate Risk
Score 2–3
Approximate 2-year CNS relapse risk: 3.4%
High Risk
Score 4–6
Approximate 2-year CNS relapse risk: 10.2%
Clinical note: The CNS-IPI is a prognostic tool and should not be used as the sole basis for decisions about CNS diagnostic evaluation or prophylaxis. Interpret results alongside disease features, patient-specific factors, institutional protocols, and specialist clinical judgment.
