ATLAS Score for Clostridioides difficile Infection
The ATLAS score predicts response to therapy in patients with C. difficile infection. Enter values measured at diagnosis or around the start of CDI therapy.
<60 = 0 points; 60–79 = 1 point; ≥80 = 2 points
<16,000 = 0 points; 16,000–25,000 = 1 point; >25,000 = 2 points
>35 g/L, or >3.5 g/dL = 0 points; 26–35 g/L, or 2.6–3.5 g/dL = 1 point;
≤25 g/L, or ≤2.5 g/dL = 2 points
Original cutoffs: ≤120 µmol/L = 0 points; 121–179 µmol/L = 1 point;
≥180 µmol/L = 2 points. mg/dL values are converted internally.
ATLAS Score
This calculator is for clinical education and decision support only.
It does not replace clinical judgment, local guidelines, or specialist input.
The original score predicted clinical cure after CDI therapy, not recurrence.
References
- Miller MA, Louie T, Mullane K, et al. Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy. BMC Infectious Diseases. 2013;13:148.
- Madden GR, German Mesner I, Cox HL, et al. Validation of Clinical Risk Models for Clostridioides difficile–Attributable Outcomes. Antimicrobial Agents and Chemotherapy. 2022.
