Age-Adjusted D-dimer Calculator for VTE
This calculator adjusts the D-dimer cutoff by age to help rule out venous thromboembolism, including suspected pulmonary embolism or DVT, in patients aged 50 years or older.
Important: This tool is for educational/clinical decision-support purposes only. D-dimer should be interpreted with clinical pretest probability. Age-adjusted D-dimer is not intended for patients with high clinical probability of VTE.
References
- Righini M, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism. JAMA. 2014.
- Douma RA, et al. Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients. BMJ. 2010.
- Schouten HJ, et al. Diagnostic accuracy of conventional or age-adjusted D-dimer cut-off values in older patients with suspected VTE. BMJ. 2013.
- American College of Emergency Physicians Clinical Policy for suspected acute venous thromboembolic disease.

