Estimates 15-year and lifetime risk for kidney donors
ESRD Risk Tool for Kidney Donor Candidates
Pre-donation Projected Risk of End-Stage Renal Disease
This model is intended for low-risk adults considering living kidney donation in the United States. It provides an estimate of the 15-year and lifetime incidence of end-stage renal disease given a set of demographic and baseline (pre-donation) health characteristics.
About This Tool
This model is intended for low-risk adults considering living kidney donation in the United States. It provides an estimate of the 15-year and lifetime incidence of end-stage renal disease given a set of demographic and baseline (pre-donation) health characteristics. It does not take into account any added risk a donor might incur due to the nephrectomy or resultant single kidney status.
The study population used to derive risk estimates included the low-risk subgroup of 7 general population cohorts with median follow up ranging from 4 – 16 years. Risk factor associations were determined using Cox proportional hazards models. Absolute risk was calibrated to annual ESRD incidence estimate derived from actual ESRD incidence from the United States Renal Data System and mortality from the United States Census.
References
- Grams ME, Sang Y, Levey AS, Matsushita K, Ballew S, Chang AR et al. Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate. NEJM 2015.
- Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med 2006;144:21-8.
- Vivante A, Golan E, Tzur D, et al. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Arch Intern Med 2012;172:1644-50.
- Mjøen G, Hallan S, Hartmann A, et al. Long-term risks for kidney donors. Kidney Int 2014;86:162-7.
- Muzaale AD, Massie AB, Wang MC, et al. Risk of end-stage renal disease following live kidney donation. JAMA 2014;311:579-86.