Duke Criteria for Endocarditis Calculator

The Duke criteria are used to rule in or rule out endocarditis. Endocarditis is felt to be present in the following conditions: 2 major clinical criteria; 1 major and any 3 minor clinical criteria; 5 minor clinical criteria. ‘Possible endocarditis’ is defined by 1 major and 1 or 2 minor clinical criteria, OR 3 minor clinical criteria. The diagnosis of endocarditis is ‘rejected’ in any of the following cases: a firm alternate diagnosis is made; clinical manifestations resolve after ≤4 days of antibiotic therapy; no pathological evidence of infective endocarditis is found at surgery or autopsy after antibiotic therapy for ≤4 days; fail to meet criteria for possible or definite infective endocarditis.