Vancomycin Dosing Calculator
This calculator estimates eGFR and provides initial vancomycin dosing recommendations.
Results
Estimated GFR (eGFR): mL/min/1.73m²
Suggested Initial Dose:
Suggested Dosing Interval:
*Disclaimer: This tool is for educational purposes only and should not be used as a substitute for professional clinical judgment. Always consult a healthcare professional.
The Vancomycin Dosing Calculator Based on eGFR is a tool that assists clinicians in determining an appropriate initial vancomycin dose and interval for adult patients. Vancomycin is an antibiotic with a narrow therapeutic window, and its dosing is highly dependent on renal function, which can be accurately estimated using both serum creatinine and cystatin C levels. The calculator uses a validated equation, such as the CKD-EPI 2021 formula, to calculate the estimated glomerular filtration rate (eGFR) and then provides dosing recommendations tailored to different levels of renal function. This personalized approach aims to optimize drug efficacy while minimizing the risk of toxicity, such as nephrotoxicity.
References:
- Inker, L. A., et al. (2021). A new equation to estimate glomerular filtration rate without race. New England Journal of Medicine, 385(19), 1737-1749.
- Rybak, M. J., et al. (2020). Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: a revised consensus guideline and recommendation. American Journal of Health-System Pharmacy, 77(11), 835-860.