Transtubular Potassium Gradient (TTKG) Calculator

Transtubular Potassium Gradient (TTKG)

This calculator estimates the TTKG, which may help assess renal potassium handling in hyperkalemia or hypokalemia.

Urine potassium (mEq/L)

Serum potassium (mEq/L)

Urine osmolality (mOsm/kg)

Serum osmolality (mOsm/kg)

Urine sodium (mEq/L)

Clinical context

TTKG

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Interpretation: –

References and Resources

West ML, et al. (1986). A strategy to evaluate hyperkalemia in the emergency department. The American Journal of Medical Sciences, 291(3), 161–168.
Ethier JH, et al. (1990). The transtubular potassium concentration gradient as a measure of the tubular response to aldosterone. American Journal of Kidney Diseases, 15(4), 309-315. View on PubMed