KDPI – Kidney Donor Profile Index
Estimates donor kidney quality and expected graft survival from donor-only factors (approximate KDPI)
For use by transplant professionals only. This calculator implements the current donor-only KDRI model and an approximate mapping to KDPI and graft survival, based on recent OPTN/SRTR guidance. It is not the official OPTN KDPI calculator and must not be used as the sole basis for allocation decisions.
Enter deceased donor details
KDRI (Rao, donor-only, unscaled): –
KDRI (scaled to median 2023 donor ≈1.0): –
Approximate KDPI: – % (–)
Estimated single-kidney graft survival (adult, US 2013–2023 averages):
• 1 year: –% |
5 years: –% |
10 years: –%
Enter all donor fields and click “Calculate KDPI” to see the approximate KDPI and expected graft survival at 1, 5 and 10 years. Values reflect population averages, not individual guarantees.
This tool uses the 2018–2021 donor-only KDRI coefficients without race or HCV terms, and a simplified mapping from scaled KDRI to KDPI and survival based on 2023 US donor data. Official KDPI values for allocation are computed by OPTN/UNOS using yearly updated reference distributions.
The Kidney Donor Profile Index (KDPI) is a numerical score (0–100%) that summarises the expected quality and longevity of a deceased-donor kidney compared with other kidneys recovered in the U.S. in a recent reference year.
It is derived in two steps:
- Kidney Donor Risk Index (KDRI) – a Cox model-based relative risk of graft failure using donor-only factors:
- Age
- Height
- Weight
- History of hypertension
- History of diabetes
- Cause of death (CVA vs other)
- Serum creatinine
- Donation after circulatory death (DCD) status
- Mapping KDRI → KDPI – the KDRI is scaled so that 1.0 corresponds to the median donor, then mapped to a percentile based on all deceased donors from the prior year. A KDPI of 80% means the donor kidney has higher expected graft-failure risk than 80% of kidneys recovered that year.
Lower KDPI = better expected kidney longevity. For example, recent OPTN data show that single kidneys with KDPI around 20% have substantially better 10-year graft survival than those with KDPI ≥ 80–90%.
What KDPI is used for
KDPI is central to U.S. kidney allocation policy and clinical decision-making:
- Helps match “longer-lasting” kidneys (KDPI ≤20%) to younger recipients.
- Helps counsel patients about trade-offs between waiting for a “better kidney” vs accepting a higher KDPI organ now.
- Provides a continuous measure of donor kidney quality, improving on the old Expanded Criteria Donor (ECD) vs Standard Criteria Donor split.
However, KDPI alone explains only a moderate amount of outcome variation (c-statistic ≈0.60), because recipient factors, surgical factors, and centre performance also matter.
⚠️ Important: KDPI is not an exact prediction of years of graft function for an individual patient.
It gives an average survival pattern for kidneys with similar KDPI, across large cohorts.
