ISTH DIC Score (International Society on Thrombosis and Haemostasis Disseminated Intravascular Coagulation score) is a standardized diagnostic scoring system used to identify overt DIC in patients with conditions known to precipitate DIC (such as sepsis, trauma, malignancy, obstetric complications, and severe systemic inflammation).

DIC is a life-threatening acquired disorder characterized by widespread activation of coagulation, consumption of platelets and clotting factors, and variable bleeding and thrombosis. The ISTH scoring system helps translate routine laboratory tests into a numerical score reflecting the likelihood of overt DIC and correlates with disease severity and mortality risk.