Harvey-Bradshaw Index (Crohn’s Disease Activity) Calculator

Harvey-Bradshaw Index Calculator – Crohn’s Disease Activity

Harvey-Bradshaw Index Calculator

Crohn’s Disease Activity Assessment Tool

What is the Harvey-Bradshaw Index?

The Harvey-Bradshaw Index (HBI) is a simplified clinical tool used to assess disease activity in patients with Crohn’s disease. Developed in 1980 as a simpler alternative to the Crohn’s Disease Activity Index (CDAI), it provides a quick and practical method for evaluating symptoms and monitoring treatment response.

The HBI is widely used in clinical practice and research to quantify Crohn’s disease activity, track disease progression, and evaluate treatment effectiveness without requiring laboratory tests or complex calculations.

Clinical Significance

Crohn’s disease is characterized by periods of remission and flare-ups with varying severity. The HBI helps clinicians objectively measure disease activity, make treatment decisions, and monitor patient progress over time. It’s particularly valuable for its simplicity and ability to be completed quickly during clinic visits.

Assessment Parameters

The HBI evaluates five key clinical parameters:

ParameterDescriptionScoring
General Well-beingPatient’s overall feeling of health0 (Very well) to 4 (Terrible)
Abdominal PainSeverity of abdominal discomfort0 (None) to 3 (Severe)
Number of Liquid StoolsDaily frequency of loose stoolsActual count per day
Abdominal MassPalpable mass in abdomen0 (None) to 3 (Definite and tender)
ComplicationsPresence of specific complications1 point each (Arthritis, Uveitis, Erythema Nodosum, etc.)

Harvey-Bradshaw Index Formula

HBI = General Well-being + Abdominal Pain + Number of Liquid Stools + Abdominal Mass + Complications

Advantages Over CDAI

The HBI was developed as a simplified version of the more complex Crohn’s Disease Activity Index (CDAI). Key advantages include:

  • No laboratory tests required
  • Faster to complete (typically 1-2 minutes)
  • Easier for patients to self-assess between visits
  • Good correlation with CDAI for clinical decision-making

HBI Calculator

Complete the following assessment to calculate the Harvey-Bradshaw Index for Crohn’s disease activity.

HBI Score: 0
Interpretation will appear here

Score Interpretation

HBI scores are categorized into disease activity levels with associated clinical implications:

HBI ≤ 4: Clinical Remission – Continue current maintenance therapy
HBI 5-7: Mild Disease – Consider optimizing current therapy or adding mild interventions
HBI 8-16: Moderate Disease – Consider treatment modification or escalation
HBI > 16: Severe Disease – Requires aggressive treatment and close monitoring

Treatment Implications

Clinical Remission (HBI ≤ 4): Continue current maintenance therapy with regular monitoring.

Mild Disease (HBI 5-7): Consider optimizing current medications, adding symptomatic treatments, or mild anti-inflammatory agents.

Moderate Disease (HBI 8-16): Often requires treatment escalation, addition of corticosteroids, or adjustment of immunomodulators/biologics.

Severe Disease (HBI > 16): Typically requires aggressive treatment with corticosteroids, biologics, or hospitalization for severe cases.

Limitations and Considerations

While the HBI is a valuable clinical tool, it should be used in conjunction with:

  • Objective laboratory markers (CRP, ESR, fecal calprotectin)
  • Endoscopic evaluation when indicated
  • Imaging studies for complications or disease extent
  • Nutritional assessment
  • Quality of life measures

Comparison with Other Indices

The HBI is one of several tools used to assess Crohn’s disease activity:

  • Crohn’s Disease Activity Index (CDAI): More comprehensive but complex; requires 7-day diary
  • Simple Crohn’s Disease Activity Index (sCDAI): Simplified version of CDAI
  • Patient Harvey-Bradshaw Index (pHBI): Patient-reported version of HBI

Note: This calculator provides an estimate based on the standard HBI calculation. Treatment decisions should always be made in consultation with a gastroenterologist considering the complete clinical picture, including laboratory results and endoscopic findings.

Harvey-Bradshaw Index Calculator – For educational purposes only. Consult a healthcare professional for medical advice.

Reference: Harvey RF, Bradshaw JM. A simple index of Crohn’s-disease activity. Lancet. 1980;1(8167):514.

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