The FLIPI (Follicular Lymphoma International Prognostic Index) is a clinical tool used to estimate prognosis in follicular lymphoma (FL) at diagnosis. It was developed in the pre-rituximab era but has remained widely used and validated in the modern treatment era as a simple way to stratify patients into risk groups based on five easily available clinical factors.
FLIPI Calculator
Follicular Lymphoma International Prognostic Index – for healthcare professionals.
This tool implements the original FLIPI definition:
1 point each for age > 60 years, Ann Arbor stage III–IV, hemoglobin < 12 g/dL,
LDH > ULN, and > 4 nodal areas involved. Risk categories:
low (0–1), intermediate (2), and high (3–5).
It is intended for educational use by trained health professionals and
must not replace clinical judgment, institutional protocols, or current lymphoma guidelines.
Patients should not use this calculator for self-diagnosis or treatment decisions.
