The Donor Risk Index (DRI) — more precisely the Liver Donor Risk Index (LDRI) — is a quantitative score that estimates the relative risk of liver graft failure based purely on donor and organ factors, not recipient disease severity.
It was introduced by Feng et al. (2006) using UNOS/SRTR data from adult deceased donor liver transplants (1998–2002). A Cox model identified donor characteristics that independently worsened graft survival; these were combined into a single log-linear index, with DRI = 1.0 defined for a “reference” ideal donor.
Liver Donor Risk Index (DRI)
Estimates relative risk of liver graft failure from donor and graft factors (Feng et al. LDRI model)
For use by liver transplant professionals only. This calculator implements the published Liver Donor Risk Index (LDRI) formula (Feng et al.) as a relative risk versus a reference donor. It does not provide an exact probability of graft failure and must be interpreted together with recipient factors and local outcomes.
Enter donor and organ details
Log-DRI sum (model linear predictor): –
Liver Donor Risk Index (DRI): –
Relative risk of graft failure vs reference donor: –
Risk band: Not yet calculated
Enter all donor fields and click “Calculate DRI” to see the relative graft-failure risk versus a reference donor, and an approximate risk band (low / moderate / high / very high).
DRI formula (Feng et al., summarized by Akkina et al.): DRI = exp{ 0.154[40–49y] + 0.274[50–59y] + 0.424[60–69y] + 0.501[≥70y] + 0.079[anoxia] + 0.145[CVA] + 0.184[other COD] + 0.176[Black] + 0.126[other race] + 0.411[DCD] + 0.422[split/partial] + 0.066(170 – height)/10 + 0.105[regional] + 0.244[national] + 0.010 × CIT(h). DRI ≈ 1.0 represents a reference donor; values >1 imply proportionally higher relative risk of graft failure.
